Image: "The Headache" by George Cruikshank (1819)
The Mayo Clinic reports that MRI scans of cluster headache sufferers had significant activity in the parts of their brains known as the hypothalamus. Just why is, again, unknown. Could it be the hypothalamus is malformed or have become damaged in some way? According to Lori K. Sergeant, MD and MichelleBlanda, MD, sometimes people suffering from cluster headaches did have a head injury in their past. But not all cluster headache sufferers have had head injuries.
eMedicine. “Headache, Cluster.” Lori K. Sergeant, MD and
Michelle Blanda, MD.